A unique blend of phytosterols, berberine and clinically studied bergamot extract to promote healthy lipid metabolism and overall cardiometabolic health.

Phytosterols are structural homologs of cholesterol that occur naturally in many plant foods. Over 30 years of research and 40 clinical trials suggest that phytosterols provide significant support for healthy lipid profiles. CholestePure Plus provides a unique blend of phytosterols, berberine and clinically studied bergamot extract to promote healthy lipid metabolism and overall cardiometabolic health. Well-established benefits of phytosterols on lipid balance stem primarily from competition with cholesterol for occupancy in micelles, particles that carry cholesterol across the intestinal epithelium into the systemic circulation. Through this mechanism, phytosterols promote excretion of cholesterol in the form of bile acids.  Research indicates that the pine-derived phytosterols offered in this formula are comparable to phytosterols from other sources. Bergamot is a citrus fruit containing two newly discovered derivatives of the flavonoids, hesperidin and naringenin. These compounds are naturally conjugated to a moiety known as hydroxymethylglutarate (HMG). In the liver, this unique molecule binds and modulates an enzyme known as HMG CoA reductase, which plays a central role in lipid biosynthesis.  These unique compounds also target enzymes, transcription factors and genes involved in lipid metabolism.*

• Promotes lipid metabolism in support of heathy lipid profiles^‡
• Supports phytosterol intake and overall cardiovascular health^‡
• Promotes healthy lipid metabolism^‡
• A unique blend of phytosterols, enhanced bioavailable berberine phytosome and clinically studied bergamot extract
• Provides enhanced-absorption berberine
• Soy-free formula
• Made with high-quality vegetarian ingredients backed by verifiable science